Video Lecture
Ketones and Brain Energy Rescue During Aging: Implication for Treating Alzheimer’s Disease
Metabolic Health Summit 2019 Video Lecture by Ketone Metabolism Expert & Researcher, Stephen Cunnane, PhD
Stephen Cunnane, PhD
Stephen Cunnane is a professor in the Department of
Medicine, University of Sherbrooke, and researcher at the Research Center on Aging.
His team is assessing the links between deteriorating brain energy metabolism and
risk of cognitive decline during aging. They were the first to show that ketones
can at least partially correct the brain energy deficit in older people at risk
of Alzheimer’s disease. This observation led to the concept of ‘brain
energy rescue’ by ketones to treat neurodegenerative disorders. In the recent 6-month
BENEFIC trial in MCI, his ketogenic medium chain triglyceride drink improved
outcomes in all five cognitive domains. It was commercialized as BrainXpert
by Nestlé in 2020 and is the first treatment available for MCI. Dr. Cunnane has
published over 350 research papers and five
books, two of which highlight the key role of ketones in brain expansion during human evolution. He was elected to the French National Academy of Medicine in 2009. In 2016, he was inducted as
a Fellow of the International Society for the Study of Fatty Acids and Lipids
(ISSFAL). He received the Chevreul Medal from the French Society for the Study
of Lipids in 2017 for his research on fats, nutrition and health.